The R package wgaim performs whole genome average interval mapping for QTL detection using mixed models. The package integrates sophisticated mixed modelling methods with a whole genome approach to detecting significant QTL's in linkage maps. Further information about the methodology can be found in the papers:
Verbyla, A. P., Cullis, B. R., Thompson, R (2007). The analysis of QTL by simultaneous use of the full linkage map. Theoretical And Applied Genetics, 116, 95-111.
Taylor, J. & Verbyla, A. (2011) R Package wgaim: QTL Analysis in Bi-Parental Populations Using Linear Mixed Models Journal of Statistical Software, 40.
Verbyla, A. P. & Taylor, J. D. (2011). High-dimensional whole genome average interval mapping and a random eff ects formulation. Theoretical and Applied Genetics, Submitted.
This package depends on the R/qtl package which can be downloaded from
http://cran.r-project.org/web/packages/qtl/index.html
